Russian researchers have demonstrated the possibility of growing tissues in microgravity conditions by conducting experiments aboard the International Space Station (ISS). Space flights not only allow us to explore new frontiers but also to develop new technologies. Among these technologies are bioprinting and the growth of human tissues, such as skin, in space microgravity. The biomaterial used for growing and printing tissues consists of cells taken from the patient. This technology allows for the creation of tissue fragments needed to cover defects, treat wounds, and help the body recover from diseases and injuries, directly aboard the spacecraft. This eliminates the need to return to Earth and enables astronauts to be treated during long-term space flights. Such flights could become a reality in the next 20-30 years. Bioprinting is no longer an innovative method, but one already actively used in biotechnology. Typically, bio-ink consists of synthetic or natural polymers, such as collagen or gelatin, mixed with living cells. The process of creating new tissues involves not only bioprinting the tissue sample but also further cultivating it in a bioreactor—a specialized device that creates conditions similar to natural ones and supplies the growing tissue with all necessary substances. Another crucial task in space conditions is ensuring food supply for astronauts. During long flights, the bioreactor could become an instrument for printing the protein-based food necessary to sustain the crew's energy levels.